Paracetamol Tablets 500mg: overview

Paracetamol, also known as acetaminophen, is a medicine used to treat pain and fever. Some popular names for paracetamol include Tylenol, Panadol, and Calpol.

Paracetamol belongs to a group of drugs called analgesics. It works by inhibiting the synthesis of prostaglandins in the body, which are associated with pain and fever. This is an effective treatment for headaches, muscle aches, arthritis, migraines, toothaches, and mild to moderate pain from injuries. It is also used to reduce fever.

Paracetamol is one of the most widely used painkillers in the world. It has been included on the World Health Organization's list of essential medicines due to its safety, effectiveness and affordability. Unlike non-steroidal anti-inflammatory drugs such as ibuprofen, which can cause stomach upset, acetaminophen is gentle on the stomach when taken in the correct dose. This is useful for people who cannot tolerate other pain relievers.

Paracetamol Tablets 500mg Active Ingredient

Paracetamol 500 mg tablets contain an active ingredient, paracetamol (acetaminophen). Paracetamol is an analgesic (pain reliever) and antipyretic (fever reducer) that works by blocking the production of prostaglandins in the body that cause pain and fever.

Each Paracetamol 500 mg tablet contains 500 mg of the active ingredient Paracetamol. Paracetamol 500 mg tablets do not contain other ingredients such as aspirin, ibuprofen, caffeine, or codeine. These tablets are made with paracetamol as the only active ingredient to control the effectiveness of the drug in treating pain and fever.

Actions of Paracetamol Tablets 500mg

Paracetamol is classified as an opioid analgesic and antipyretic. It works by blocking the synthesis of prostaglandins, chemicals produced in response to injury that cause pain and fever. In particular, acetaminophen inhibits the production of prostaglandins by cyclooxygenase (COX) in the central nervous system.

There are two types of cyclooxygenases - COX-1 and COX-2. Nonsteroidal anti-inflammatory drugs (NSAIDs) such as aspirin and ibuprofen inhibit COX-1 and COX-2. This nonselective inhibition is why NSAIDs produce side effects such as diarrhea and gastric ulcers.

However, acetaminophen inhibits COX-2, a protein that produces prostaglandins associated with pain and inflammation. Inhibiting COX-2 allows acetaminophen to provide analgesia and antipyretic effects without the gastric problems of NSAIDs. However, the exact mechanisms involved in the selection of acetaminophen are not fully understood.

Paracetamol is less effective than NSAIDs. Paracetamol is also a better pain reliever than opioids, acting directly on the central nervous system. However, when sedation is not required, paracetamol is often recommended as the first-line treatment for mild or moderate pain. It is important to avoid nonsteroidal anti-inflammatory drugs, for example in patients with stomach cancer or blood disorders.

Paracetamol Tablets 500mg Uses and Indications

Paracetamol tablets are widely used to treat a variety of pain conditions. Some uses and indications of paracetamol tablets are as follows:

Headaches - Paracetamol is very effective in treating headaches, migraines and cold-related headaches, as well as sinusitis. It reduces inflammation and prevents scalp tension that causes headaches.

Muscle Pain - Paracetamol relieves pain associated with muscles and joints. Some of these include colds, arthritis, stress, sprains, and muscle pain from exercise.

Back - Back pain can be debilitating, and paracetamol can help reduce swelling and pain. It can help relieve low back pain, sciatica, and pain after strenuous exercise

Dentistry - Toothache and pain caused by procedures such as root canals and tooth extractions can be treated with paracetamol tablets. This therapy can relieve muscle and joint pain.

Cough and fever - Paracetamol is an antipyretic, which means it reduces fever. It treats the symptoms of colds, flu, and other illnesses that are accompanied by fever and body aches.

Therefore, paracetamol tablets are an analgesic that can treat many problems related to aches, pains, headaches, and fever. This is one of the medications used to treat these symptoms.

Dosage and Administration of Paracetamol Tablets 500mg

Paracetamol is usually taken by mouth. The adult dose is 500-1000 mg every 4-6 hours, up to 4000 mg per day.

The maximum daily dose for adults and children over 12 years of age is 4000 mg. Exceeding this level increases the risk of liver disease.

Paracetamol should be taken with food and milk to relieve stomach pain.

For children under 12 years of age, the dose is 10-15 mg per kilogram of body weight, given every 4-6 hours as needed. The maximum daily dose for children is 60 mg per kilogram of body weight.

In elderly patients, no dose adjustment based on age alone is necessary. However, older patients may be more sensitive to side effects. Consider starting with a low dose and titrate based on response and tolerability.

Patients with liver problems should not take more than 2 grams per day. Patients with severe liver disease or severe hepatic disease should avoid the use of acetaminophen.

Do not take paracetamol or other medicines containing paracetamol to avoid exceeding a safe dose. Always check the medicine label to make sure paracetamol does not mix with other products you take.

Taking paracetamol for several days in a row increases the risk of liver damage. Do not use for more than 10 days if you have pain or more than 3 days if you have fever without consulting your doctor.

Warnings and Precautions of Paracetamol Tablets 500mg

Acetaminophen is generally safe when taken at recommended doses. However, there are some warnings to be aware of:

Liver damage - Too much acetaminophen can cause liver damage. The maximum daily dose for adults is 4,000 mg. Taking too much can interfere with the liver's ability to process the drug properly. People with liver disease are at increased risk of developing liver cancer.

Avoid overdose - It is important not to take more paracetamol than prescribed or more than four hours apart. Check your prescription carefully to avoid increasing the dose of paracetamol found in many products. Medications can severely damage the liver.

Medication Use - Paracetamol can interact with other medications such as warfarin, carbamazepine, phenytoin, isoniazid, rifampicin, and St. John's wort. Check with your doctor before taking acetaminophen with this medication as the dosage may need to be adjusted. You should also avoid drinking alcohol while taking paracetamol.

To avoid possible problems, be sure to read and follow dosing instructions. Be careful with all other medications and supplements you are taking. In case of overdose, seek medical assistance. When used as directed, acetaminophen is effective and well tolerated. But the warning is not to exceed the prescribed dose.

Side Effects of Paracetamol Tablets 500mg

Paracetamol is generally well tolerated when taken at acceptable doses. However, some side effects may occur.

Paracetamol Side Effects:

Abdominal Pain

Diarrhea

Headache

Anxiety.

Headache

Anxiety

Neglected difficulty sleeping. If this condition persists or bothers you, talk to your doctor.

Main effects

Sometimes, paracetamol can cause side effects, such as:

Liver damage - Regular use of paracetamol, even at the correct dose, can cause liver damage. Symptoms include yellow skin/eyes, itching, abdominal pain.

Low platelet count (thrombocytopenia) - This causes increased bruising or bleeding.

Kidney disease - Paracetamol may worsen kidney problems in some individuals. Symptoms include decreased urination, swelling, fatigue.

Severe skin reactions - Blistering, peeling, hives, rash.

Anemia - Fatigue, pale skin, heart palpitations, shortness of breath.

If you experience any side effects, stop taking paracetamol immediately and seek medical advice. These are signs of an allergic reaction or the need for immediate treatment.

Symptoms and Treatment

Too much acetaminophen (the active ingredient in paracetamol) can damage the liver. Acetaminophen overdose is a major cause of liver disease in many parts of the world.

Other symptoms of acetaminophen overdose include:

Nausea, vomiting,Loss of appetite.

Abdominal pain and cramps,Pale skin.

Sweating fatigue,Mild Dizziness and confusion.

Facial fatigue and weakness 4 Skin and weakness and weakness.

Taking too much acetaminophen over several days may cause liver damage. Even if you do not experience the first symptoms after an acetaminophen overdose, it is important to get emergency medical assistance. If left untreated, acetaminophen toxicity can lead to liver failure.

A drug that prevents liver damage if taken within 8-10 hours of acetaminophen administration. This product helps restore glutathione, a natural antioxidant that reduces liver damage. It is important to use this medication correctly.

Emergency room physicians may also give medications and intravenous fluids to prevent kidney damage associated with acetaminophen poisoning. In severe cases, if liver failure occurs, a liver transplant may be required.

If you suspect you have overdosed on acetaminophen, be sure to seek emergency care immediately. Early treatment can prevent liver damage and save lives.

Storage and Handling of Paracetamol Tablets 500mg

Paracetamol

Tablets should be stored at room temperature, away from excessive heat and moisture. Store the medicine in a cool, dry place with a temperature below 30°C. Do not refrigerate or freeze acetaminophen tablets.

When it comes time to dispose of unused or expired paracetamol tablets, it is important to handle them correctly and safely. Flushing chemicals down the toilet or sink can contaminate the water. The best way to get off paracetamol is to use a prescription or bottle of your choice. Check with your pharmacy, health department or waste service to find an approved collection point in your area.

If you don't have a recycling program, place pills and other nuisances (like cat litter or coffee grounds) in a sealed plastic bag. Please remove personal information from the packet before discarding it. Do not break tablets before throwing them away. Paracetamol and other medications should not be flushed down drains or toilets. Proper disposal protects the environment and prevents chemicals from falling into the wrong hands.

Conclusions

Paracetamol, taken in appropriate doses, is considered a safe and effective medication for the treatment of minor pain and the reduction of fever in adults and children. Paracetamol provides analgesia and antipyretic effects by inhibiting the COX enzyme involved in prostaglandin synthesis. It does not fight inflammation like nonsteroidal anti-inflammatory drugs.

Adults and children over 12 years old can take 1 gram every 4-6 hours, no more than 4 grams per day. Reduce pediatric dose based on weight/age.

Avoid exceeding dosage limits as it may cause serious hepatic injury. Do not take with other medicines containing acetaminophen.

Adverse skin reactions are rare but require immediate attention. Other side effects are rare.

Overuse requires immediate medical attention as it may cause organ damage and death. If taken early, N-acetylcysteine can help prevent liver damage.

Clear unused frames. Do not store or take old paracetamol that has expired.

Overall, acetaminophen is an effective over-the-counter medication if dosage instructions are followed. Consumers should use acetaminophen with caution, be aware of all ingredients in the mixture, and avoid exceeding the prescribed dose. If severe symptoms occur, seek medical assistance immediately.

What is paracetamol?

Paracetamol, also known as acetaminophen, is a medicine used to treat pain and fever. Some popular names for paracetamol include Tylenol, Panadol, and Calpol.

Paracetamol belongs to a group of drugs called analgesics. It works by inhibiting the synthesis of prostaglandins in the body, which are associated with pain and fever. This is an effective treatment for headaches, muscle aches, arthritis, migraines, toothaches, and mild to moderate pain from injuries. It is also used to reduce fever.

Paracetamol is one of the most widely used painkillers in the world. It has been included on the World Health Organization's list of essential medicines due to its safety, effectiveness and affordability. Unlike non-steroidal anti-inflammatory drugs such as ibuprofen, which can cause stomach upset, acetaminophen is gentle on the stomach when taken in the correct dose. This is useful for people who cannot tolerate other pain relievers.

What is Paracetamol tablets 500mg Side Effects?

Paracetamol is generally well tolerated when taken at acceptable doses. However, some side effects may occur.

Paracetamol Side Effects:

Abdominal Pain, Diarrhea.

Headache, Anxiety.

Neglected difficulty sleeping. If this condition persists or bothers you, talk to your doctor.

Product Specifications:

paracetamol tab 500mg

SKU“stock keeping unit”:2024.par05001

gtin14:20231111001005

Price:0.49 - 1.19$.

Price Currency: USD

Price Valid Until:"2026-11-20

paracetamol tab 500mg

paracetamol tab 500mg

paracetamol tab 500mg

Dosage:500mg.

Active Ingredients:paracetamol.

Specifications:BP；USP.

Packaging:；10.

Registration:

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